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心血管系統

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產品簡介:
        遺傳性心血管panel是利用目標區域捕獲與新一代基因分析技術,對遺傳性心血管疾病相關基因區域進行分析和生物信息學分析,結合病史、癥狀表現及心電圖信息,可在早期篩查出有心血管疾病的患者,同時也為患者實現個體化藥物使用提供重要依據。
        遺傳性心血管產品包含多種疾病的基因分析,如長QT綜合征(LQTS)、短QT綜合征(SQTS)、Brugada綜合征(BrS)、兒茶酚胺敏感性多形性室速(CPTV)、Loeys-Dietz綜合征、家族性陣發性心室顫動、法洛四聯癥、耶維爾-朗厄·尼爾遜綜合征、遺傳性冠狀動脈疾病等。

技術優勢:
        1、準確高效:使用新一代基因分析技術,具有高精度、高分辨率、高靈敏度、高通量的特征,克服傳統PCR技術通量低的缺點;
        2、結果全面:可一次性分析多種相關基因的突變,并得出對應的發病類型,信息更全面;
        3、分析智能:高性能的計算平臺,自動化流程,保證分析結果的可靠性;
        4、前瞻性高:可發掘新的致病基因和突變位點,也適用于科研合作項目。

技術流程:
 
圖1 心血管系統疾病基因捕獲實驗流程
 
適用人群:
       
1、早期發現致病基因,及早采取干預措施,降低發病率;
        2、輔助專家根據癥狀分析,為后續研究制定合理的方案;
        3、明確家族中其他致病基因攜帶者,徹底消除家族中這類疾病帶來的危害;
        4、為亞健康人群及健康人群進行風險預測和評估,提供后期的預防保健咨詢。
    

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